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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b5841b7943887474d44cb87207860e0f44d4123f3386c84567ae9b254ae8f2d' 
  AND token = '3YkjQVmL1suxCwaHtiSvK0m9+mYt6JfC9LcjCRC9iXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}