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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efa24bbd0058b8cc3c1a82da5d945deb9a1b1a3728a204c0f1a2b3d606b0223f' 
  AND token = 'Lsv/XJ/4f+E2eIYwaYwF+UvtIwPX4gA302e5dqRD5FA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}