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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ed001a73c111e550007f850a705d8f499023c5e8e81b68fc2d2de454102ac02' 
  AND token = 'Vipb/WBl/a/7J0DJCjt+K5Tl6MbJZBMG9bxjLgjls8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}