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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c2e5729c481b6c831221d2afb8148e3b14e18ed4925671deaf0142f2e76fec6' 
  AND token = 'Cg106dVYz8QICIx/02i3ptSVToby6bI37k2zzL9AfCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}