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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3223585d13bb87d9ba8ecf02e8a447158f4bce896db0bb6255be93622ed0573' 
  AND token = 'JBsA93Ag4BI27t9H6WgFmVH5coXOs0Nr/kJetzCKBno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}