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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc0bb99e5f62d2aaa9d8d9e27a846be17666f15b8e7eb60f16399c799edb6e0a' 
  AND token = 'PFPJT8CR+Z4zu9/DtQbVKzuJU5GZk2Yy59PB9qLmPPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}