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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec3fd0158c632d67b38d97a33b0de0a3d456ee384099be1c33d6bebeae647af3' 
  AND token = 'T4PHktYuBcXM94xENu1ajB8rdXbpGUkLDnqu/ET7aPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}