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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a40148d2ae51181cf3414205cbc78bc3a6b1192219b45ccb47acf535d95b074' 
  AND token = 'FTfDrJWPdFYgiMR9qE8PUKSgAgfsvba3a3Dwx8H0bVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}