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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '149266f8ffda159ff27a52967e3ba44323e3fb82db3065b8846f524ba2b93557' 
  AND token = 'iWj2lqH5Y2XHvNVMQRxW0dzzDInCfdRn4lTYzfKpgpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}