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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42fb37db0fdcbbe2a8ccc830e0e1acabafb36625411f7fcafe75ed7a41c1930f' 
  AND token = 'vuuF1Hpf571VkrXZeHtIvUDov+4d1bt7Cr7IhoJMgAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}