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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '979ca6b2531e23e623a0334e667f0d24b10f281fbfbf7c46adfdadf52ae18157' 
  AND token = 'lIpwI5HK4rv7WUVGI5b0+LxCpYQP281tWcLBi6vyftg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}