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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '498c334618dbcd70f34fd6d70f839587a5a33cd0ec77adfbc7d744a8faf890eb' 
  AND token = 'PkCV0OcioaWuTywdFJoT5cwGxvbv6gF3+wNPH/ZUyMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}