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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8937e8f67c85bc2f4b23baeee34d6c29b8dbbf3ed740bc5e13c5cb7e58bd6e3c' 
  AND token = '/eyMTaBPAP+zLexcorP5eKSkUhCVoDY5tcTXNwTcqfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}