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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f26f1f6ef749a938b703f16a84716f6c7af5df5fb1ee3545d1089e5336c8b39' 
  AND token = 'grC7wfMh30rguW0WaPraQemVhpQtsRaKuUv0VNKhnmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}