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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cd1858d49a9ec871aec617a45bbe6f82407a17f9091c8a2ccc62ef6b00598fd' 
  AND token = 's4yGnawSrRz0M0f8b+dN/k0JyXbcGHt+fVEszv81Geg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}