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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4803e185d55429511664cb59611438c78a052bb217f777004bd421c09a52db47' 
  AND token = 'uaDb33FbgeTDO1CU8QhJxQmbBTx08gfuI1fXumJBUdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}