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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f517b8ba7c52449a87a600e4b360d02eb3636b20fac0945017076700d5f8005' 
  AND token = 'QEALw0R9cc3cHFbL/4nldqwScE3gc6GG3Y/1CZkNfP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}