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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bfd7f1cdaf2dfe6413ca32bbac1439107e8723804aace91320d6cdf17b0390e' 
  AND token = 'IEhLW+W7eSsAMh9rmHr4pFVyFXcTDZXKXNbYuJsrSFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}