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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '409b041df9401f260eeb3760f9d82ddd0170aa0b65f071d2b1d5306be032e2d4' 
  AND token = 'K0KssoybGkkGrRg1ZWxQYwnXIbCBIycFJ0fKNXido2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}