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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9f910a26b6b461699cb4cf2f701881c19481c910525c27f20256eeead796b66' 
  AND token = 'RA5+B+VS2n+NjkKPQSusk1tjVlptN5M6DHQk29SPIXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}