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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75f17ca305e31060469f30527edc647f55bc12f4cb6000f9d0d5a765df096e90' 
  AND token = '0PGuYBV5J1Tn9BPJYzk0XFtg9vVQW7pghrWGHmhtO+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}