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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5d4fe01dca390b22828d385ceebfefe28dcdc603ab9fbe3297a24870e31f589' 
  AND token = 'ZZ2QHPtboHMGN4/gqsqPPG50UUB8nIFKxNTI+QYbKoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}