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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed4d74ccadd4222370747bbfca78918ad217ee9e0e048f44d1a4f04e8e09e963' 
  AND token = 'i5eSZguYH2s5CiIrFmjyi2zxDqh9B+3pcjs/4p7SbdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}