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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c73c9d4addd85434c83ce740a60d5267cb70a17d27f9f9127df2de5abcec51f1' 
  AND token = 'GrJLjtjU5c5+e0mZhsRVSlFpxYDyCWmkZelb+FBOo4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}