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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e47b00eb4fd81c7567acdbc4e2aac87f1c7745f07835452f29f53584ca4fe68' 
  AND token = 'Wa2ET65+mvKb5OYtHv4odFaMsX8VnWRw6RGdwHBCELw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}