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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '604785c50a9e52826184abd68e9792530cd9aeb0ea54cfe1a02bc9b1f8c2b332' 
  AND token = '8Lxo7ubH8jnhbMyz5BiJlixu+ilZigEmzRSL3x3WE8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}