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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69853bc94311f0f1bdda2b1674b501ada4318bfbe1e0be9364bd72aa3cd77e3a' 
  AND token = 'sfeChXvtq3VZpdZu4rYAfZZeJ0Ey52BNQlpme8UNFU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}