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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9387d21c3bd47d37bf2610fbcdcf991731701016279fd8e93741790cacb3dd7b' 
  AND token = 'QXpPRrYt6cedi09NSxHtZNhe6hSg1nrNeWvyA2p8wk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}