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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7625d135655ac50482b9b45fe90bc580316147f9c97c65ffe76214c0b8ad086f' 
  AND token = '6Wj0xFA8Jb/JEhwShan9a0tOaR3uBcPCbPNfiNqcHfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}