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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd3e36ae83a44efb1c9662abdfd8698170297081b89041497c81bdc109919a21' 
  AND token = '2NHwk0Bzk+7nqonakRnPu2P3cMxyE9Y+I1rsj+VDMVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}