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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9189e1a713e7ac353c9c123db88f6e4cce2e4c12a68d828d232a3b69da0401c9' 
  AND token = 'P6PXIU1j6ROB2eQqBq5qcZTHYvjWK1mRTQb6gnKl3WI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}