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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5a3aa03dfc11432fdf3b05d28d2917776dc09644635b4643dae64a5a7c68532' 
  AND token = 'qiPVq4+FegSMNuexn/8VkTor+nooKgl7DcQd+VNWHFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}