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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ed4a2396b296847c0e15e3aa17e1e107217f84577c0b7750683257bad79d63a' 
  AND token = 'O13gIkv9uc2JHLSTb3GDwwwkAW3SgNsvmYwTy5aKwTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}