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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2defddd4d9530b51129b82c8b349f4a424b98a537f16b50bdf0b93892963d3a1' 
  AND token = 'lX9TNmkbYQkRFgbAKlPE2pvq0xdy4vpyAVaFxXqYFDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}