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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '577f6c7d0e439e03d2f7bddd9ebd9ea81c8663c9245d46341ecced06bbb75806' 
  AND token = 'XerzadXu0PYOo+vB2+pAUQQS4/E2Tc0fji3YuQiXGW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}