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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7290b7ffec536b4b3932af69d83dfd19e07d91e74fef35bf788a545d6457fa3d' 
  AND token = 'hYuFWrICWz4UARk7Lz5fSiWMXigv3VuV3XYUUrKQ8+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}