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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd95dbdf5a51605263dae2c0d32a94a24876c4a9180a7b869c0f227cfca21797c' 
  AND token = '6fzvd+buKkASqb722QqwSCaBazYLuAsZzkpvgoNZyw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}