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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ca8fc2458aa898aa22e95ac4c36794a6d043281c847502a54476da9dc2a1e0c' 
  AND token = 'DiEwf56YVgKNm8a0RaIKxykEMok3X6KR7BrihEB1sAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}