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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ad22ac3ae67cda93ab65fb0d1648765f31540a15137e8c0f64a0e9576b5688c' 
  AND token = 'y0NATa8X9RgZCNTDO46l0Nt3t5xu0gdtKe8BzhElktY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}