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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ef3082a8138944b11a3985e6e1a17d4a071316680421f939a0d37fc913c0549' 
  AND token = 'qKfe6W+H24Y12PITQwaVE468K0uHnwdjC+iFly1snc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}