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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca22289bbdd767ff5ddab62d462016600950cb73b10be2129567b77309c942f8' 
  AND token = 'F3u0GX5tf9nUpgO/xeHcH3/Wk+ZIbk4q81cEt75iPV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}