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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b364355c7fc2877c2cbc27c4086f5a07e7a762633e06ef9a4735bb9c39429965' 
  AND token = 'XtHmkQLTU9wU7wKQLnUJ/c2xfmnlnHPHaan/meWV8F8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}