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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e74572880449a2926c9342141afdc8655f7c866a202e8d26d59f2862fc164b06' 
  AND token = 'p0xrs0DEQhTaC2Eg+tbbk67yzpUlCQHCApbAXByBzzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}