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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a826f7e3d5e005fd4314725ed77ca368a75bf51cbfc0b43ed6bd1ced0e488024' 
  AND token = 'So17JtgIOc2fmqDEikB2M7s+jlRJfHPY/SX+biOnvWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}