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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6521ac3c5d3d6e4dca91896596ecf86acb36d61f5db33a9a0feda66ada6c2e53' 
  AND token = 'zhfrzuv8KFXKMJuLipoF4Kf6S2xx7DH11sr28jMGNnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}