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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b9d1eec9f323b5d3aaf1b949333fade7fd146ecb0fefed3b25eb7ee0ba16606' 
  AND token = 'tPLg/dDsnvIzXXIFPU7hUtxDlt6rqmCmjB+f+W9Dg+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}