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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f81f50cce6c0ccb0b294b570f1f92347563d008fea2a672cbf0836b8bc783ad9' 
  AND token = 'Hvcwg0KBiclH3MfXumb6jxpWBFKtrBdujDwzbg1JAPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}