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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81e2855f2eca10f4cc244e8b643c8833be29fa97d938f1b49562dc2060e95027' 
  AND token = 'dldGtwRx8H1dlOPH4sU8pm5M6PkH0g4TcYt3wDlD8rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}