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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e367211404c3ce53c4a50809399eba72d9b8f78ac465140c7b32512c72da05aa' 
  AND token = 'MlThmYSEiTmZtt06ptlJNeMQVNlDO9gtFMYD1regNsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}