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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d3aef3cc52767dfc84c103ceac6ff95e864cd1f3d886ca2c7b0ef41815e2340' 
  AND token = 'FihfuVOK3vT4sz77QG/1MkN2EWZh+fb6WfP/QMVbKgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}